ALIMTA PACKAGE INSERT PDF

ALIMTA (pemetrexed for injection) [package insert]. Indianapolis, IN: Eli Lilly and Company; Langer CJ, et al. Lancet Oncol. ;17(11) Learn how ALIMTA may help treat advanced nonsquamous non-small cell lung cancer. ALIMTA and carboplatin (carbo) is approved by the FDA to be used with an the FDA in combination with carboplatin (another chemotherapy drug) and. Read all of this leaflet carefully before you start receiving this medicine because it contains important information for you. -. Keep this leaflet. You may need to.

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To view the most recent and complete version of the guidelines, go online to NCCN.

Tell your healthcare provider right away if you get any new or worsening symptoms of shortness of breath, cough, or fever. Monitor patients for inflammation or blistering in areas of previous radiation treatment.

ALIMTA is contraindicated inwert patients who have a history of severe hypersensitivity reaction to pemetrexed.

ALIMTA® (pemetrexed for injection) | Official healthcare professionals site

There is no information regarding the presence of pemetrexed or its metabolites in human milk, the effects on the breastfed infant, or the effects on milk production. Go to data for additional indications.

Based on Kaplan-Meier estimation.

Like cisplatin, carboplatin contains platinum. Adverse reactions observed in insfrt patients studied were similar to those observed in adults. This indication is approved under accelerated approval based on tumor response rate and progression-free survival. Hold on longer to what matters most. Folic acid and vitamin B 12 supplementation should be continued during treatment and for 21 days after the last dose of ALIMTA as they may reduce the severity of treatment-related hematologic and gastrointestinal toxicities.

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Tell your healthcare provider right away if you have a decrease in amount of urine. The risk of myelosuppression is increased in patients who do not receive alomta supplementation. It is very important to take folic acid by mouth and receive vitamin B 12 injections from your healthcare provider during your treatment with ALIMTA to lower your risk of harmful side effects.

Males packagge Reproductive Potential: Your healthcare provider will do a blood test to check your blood cell counts regularly during your treatment with ALIMTA. Talk to packgae healthcare provider if this is a concern for you. Withhold ALIMTA for acute onset of new or progressive unexplained pulmonary symptoms such as dyspnea, cough, or fever pending diagnostic evaluation.

If you are allergic to pemetrexed, tell your packwge because you should not receive it. You are encouraged to report negative side effects of prescription drugs to the FDA. Langer CJ, et al. Tell your healthcare provider right away if you develop blisters, skin sores, skin peeling, or painful sores, or ulcers in your mouth, nose, throat or genital area.

Severe vomiting or diarrhea can lead to loss of fluids dehydration which may cause kidney problems to become worse. It is not known whether these effects on fertility are reversible. ALIMTA can cause severe myelosuppression resulting in a requirement for transfusions and which may lead to neutropenic infection.

Low blood cell counts can be severe, including low white blood cell counts neutropenialow platelet counts thrombocytopeniaand low red blood cell counts anemia. This may affect your ability to father a child. Call your doctor for medical advice about side effects.

Indications and Important Safety Information. Indications and Important Safety Information.

ALIMTA® (pemetrexed): Storage of Unreconstituted Vials

Overall response rate a ORR: ALIMTA is indicated as a single agent for the maintenance treatment of patients with locally advanced or metastatic nonsquamous non-small cell lung cancer NSCLC whose disease has not progressed after four cycles of platinum-based first-line chemotherapy. It is not known if these effects are reversible.

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The incidences of Grade anemia, fatigue, thrombocytopenia, hypertension, and neutropenia were higher in patients 65 years of age and older as compared to inseft patients: If concomitant ibuprofen use cannot be avoided, monitor patients more frequently for ALIMTA adverse reactions, including myelosuppression, renal, and gastrointestinal toxicity. Kidney problems, including kidney failure. NCCN makes no warranties of any kind whatsoever regarding their content, use, or application and disclaims any responsibility for their application or use in any way.

Based on findings from animal studies and its mechanism of action, ALIMTA can cause fetal harm when administered to a pregnant woman. Packave GV, et al. Continued approval for this indication may be contingent upon paclage and description of clinical benefit in the confirmatory trials.

Accessed June 27, The infusion is given over 10 minutes. Your packxge provider will prescribe a medicine called a corticosteroid for you to take 2 times a day for 3 days, beginning the day before each treatment with ALIMTA.

ALIMTA® (Pemetrexed) and Pharmacokinetics

Tell pafkage healthcare provider if you have kidney problems and take a medicine that contains ibuprofen. Based on high-level evidence eg, randomized controlled trials and there is uniform NCCN consensus that the intervention is appropriate. For more information, ask your healthcare provider or pharmacist.

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